Archive for the ‘magnesium’ Category
Magnesium and Chronic Fatigue Syndrome – Study
June 17th, 2010 | 
Author: Two recently published studies suggest that a possible organic explanation for Chronic Fatigue exists.
British scientists report that low levels of magnesium may play a part in this illness of unknown cause. Although it is unclear whether magnesium injections reported improvements in their condition. The findings were published in the March 30 issue of “The Lancet” a renowned British medical journal.
The studies were conducted by Dr. Michael J. Campbell, a medical statistician at Southampton General Hospital. Ivan M. Cox, a medical student at the University of Southampton and Dr. David Dowson, a Southampton physician.
“This study shows a dramatic improvement in a small group of people with this illness, but it is too soon to say that this is an appropriate treatment that will be of help to the vast majority of patients,” said Dr. Jay A. Levy, a professor of Medicine at the University of California at San Francisco, who has been searching for a possible viral cause of the disease.
Chronic fatigue patients usually complain about malaise lasting several months or years and nonspecific flu-like symptoms, including headaches, fever and muscle pain. They also suffer from an inability to think clearly, irritability and depression.
The researchers said they had decided to explore magnesium levels in patients with chronic fatigue because malabsorption of magnesium had been associated with lethargy and weakness. They did a case study and found that 20 patients suffering from chronic fatigue had slightly lower red-cell magnesium concentrations than did 20 healthy subjects matched for age, sex and social class.
In a clinical trial involving 32 patients with chronic fatigue syndrome, 15 patients were randomly given intramuscular injections of magnesium sulfate every week for six weeks and 17 were given shots of water.
The patients were not aware which treatment they were receiving. Before and after the treatment, patients completed a questionnaire asking about their energy levels, pain, perception, sleep patterns, sense of social isolation, emotional reactions and physical mobility.
Twelve of the 15 patients treated with the magnesium said they had benefited and reported higher energy levels, better emotional states and less pain: just three patients who received the dummy shots claimed any improvement.
Yet to be determined is why magnesium levels were so low in these patients and if this is the case in the majority of chronic fatigue patients. Doctors have only recently started to take chronic fatigue syndrome seriously after years of dismissing it as little more than a figment of a patient’s imagination.
http://www.mgwater.com/chroniclz.shtml
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Tags: CFS, Chronic Fatigue Syndrome, depression, Headache, Lethargy, muscle pain, Weakness | 
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Magnesium in the management of asthma
Harari M, Barzillai R, Shani J.
The recognition of asthma as an inflammatory disease has led over the past 20 years to a major shift in its pharmacotherapy. The previous emphasis on using relatively short-acting agents for relieving bronchospasms and for removing bronchial mucus has shifted toward long-term strategies with the use of inhaled corticosteroids, which successfully prevent and abolish airway inflammation. Because some of the biological, chemical, and immunological processes that characterize asthma also underlie arthritis and other inflammatory diseases, and because many of these conditions have been successfully treated for the past 40 years at the Dead Sea, we were not surprised to realize and record the significant improvement of asthmatic condition after a 4-week stay at the Dead Sea: lung function was improved, the number and severity of attacks was reduced, and the efficacy of beta2-agonist treatments was improved. After reviewing the acute and chronic treatments of asthma in the clinic (including emergency rooms) with magnesium compounds, and the use of such salts as supplementary agents in respiratory diseases, we suggest that the improvement in the asthmatic condition at the Dead Sea may be due to absorption of this element through the skin and via the lungs, and due to its involvement in anti-inflammatory and vasodilatatory processes”.
Abstract from a scientific study at DMZ Rehabilitation Clinic, Ein-Bokek, The Dead Sea, Israel)
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Tags: anti-inflammatory, arthritis, asthma, bronchail mucus, bronchitis, Inflammation |
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MAGNESIUM CHLORIDE IN ACUTE AND CHRONIC DISEASES
By Raul Vergini, M.D.
Back in 1915, a French surgeon, Prof. Pierre Delbet, M.D., was looking for a solution to cleanse wounds, because he had found out that the traditional antiseptic solutions actually mortified tissues and facilitated the infection instead of preventing it.
He tested several mineral solutions and discovered that a Magnesium Chloride solution was not only harmless for tissues, but it had also a great effect over leucocytic activity and phagocytosis; so it was perfect for external wounds treatment.
Dr. Delbet performed a lot of in vitro and in vivo experiments with this solution and he became aware that it was good not only for external applications, but it was also a powerful immuno-stimulant if taken by injections or even by mouth. He called this effect “cytophilaxis”. In some in vivo experiments it was able to increase phagocytosis rate up to 300%. Dr. Delbet serendipitously discovered that this oral solution had also a tonic effect on many people and so became aware that the Magnesium Chloride had an effect on the whole organism.
In a brief time, he received communications of very good therapeutics effects of this “therapy” from people that were taking Magnesium Chloride for its tonic properties and who were suffering from various ailments.
Prof. Delbet began to closely study the subject and verified that the Magnesium Chloride solution was a very good therapy for a long list of diseases.
He obtained very good results in: colitis, angiocholitis and cholecystitis in the digestive apparatus; Parkinson’s Disease, senile tremors and muscular cramps in the nervous system; acne, eczema, psoriasis, warts, itch of various origins and chilblains in the skin. There was a strengthening of hair and nails, a good effect on diseases typical of the aged (impotency, prostatic hypertrophy, cerebral and circulatory troubles) and on diseases of allergic origin (hay-fever, asthma, urticaria and anaphylactic reactions).
Then Prof. Delbet began to investigate the relationship between Magnesium and Cancer. After a lot of clinical and experimental studies, he found that Magnesium Chloride had a very good effect on prevention of cancer and that it was able to cure several precancerous conditions: leucoplasia, hyperkeratosis, chronic mastitis, etc.
Epidemiological studies confirmed Delbet’s views and demonstrated that the regions with soil more rich in magnesium had less cancer incidence, and vice versa.
In experimental studies, the Magnesium Chloride solution was also able to slow down the course of cancer in laboratory animals.
Prof. Delbet wrote two books, Politique Preventive du Cancer (1944) and L’Agriculture et la Santé (1945), in which he stated his ideas about cancer prevention and a better living. The first is a well documented report of all his studies on Magnesium Chloride.
In 1943 another French doctor, A. Neveu, M.D., used the Magnesium Chloride solution in a case of diphteria to reduce the risks of anaphylactic reaction due to the anti-diphteric serum that he was ready to administer.
To his great surprise, when the next day the laboratory results confirmed the diagnosis of diphteria, the little girl was completely cured, before he could use the serum.
He credited the immuno-stimulant activity to the solution for this result, and he tested it in some other diphteric patients. All the patients were cured in a very short time (24-48 hours), with no after-effects. As Magnesium Chloride has no direct effect on bacteria (i.e.it is not an antibiotic ), Neveu thought that its action was a specific, immuno-enhancing, so it could be useful, in the same manner, also against viral diseases.
So he began to treat some cases of poliomyelitis, and had the same wonderful results. He was very excited and tried to divulge the therapy, but he ran into a wall of hostility and obstructionism from “Official Medicine”. Neither Neveu or Delbet (who was a member of the Academy of Medicine) was able to diffuse Neveu’s extraordinary results. The opposition was total: Professors of Medicine, Medical Peer-Reviews, the Academy itself, all were against the two doctors. “Official Medicine” saw in Magnesium Chloride Therapy a threat to its new and growing business: vaccinations.
Dr. Neveu wasn’t discouraged by this and continued to test this therapy in a wide range of diseases. He obtained very good results in: pharyngitis, tonsillitis, hoarseness, common cold, influenza, asthma, bronchitis, broncho-pneumonia, pulmonary emphysema, “children diseases” (whooping-cough, measles, rubella, mumps, scarlet fever…), alimentary and professional poisonings, gastroenteritis, boils, abscesses, erysipelas, whitlow, septic pricks (wounds), puerperal fever and osteomyelitis. But the indications for Magnesium Chloride therapy don’t end here.
In more recent years other physicians (and I among these) have verified many of Delbet’s and Neveu’s applications and have tried the therapy in other pathologies: asthmatic acute attack, shock, tetanus (for these the solution is administered by intravenous injection); herpes zoster, acute and chronic conjunctivitis, optic neuritis, rheumatic diseases, many allergic diseases, spring-asthenia and Chronic Fatigue Syndrome (even in cancer it can be an useful adjuvant).
The preceding lists of ailments are by no means exhaustive; maybe other illnesses can be treated with this therapy but, as this is a relatively “young” treatment, we are pioneers, and we need the help of all physicians of good will to definitely establish all the true possibilities of this wonderful therapy.
From a practical standpoint, please remember that only Magnesium CHLORIDE has this “cytophylactic” activity, and no other magnesium salt; probably it’s a molecular, and not a merely ionic, matter.
The solution to be used is a 2.5% Magnesium Chloride hexahydrate (MgCl2-6H2O) solution (i.e.: 25 grams / 1 liter of water).
Dosages are as follows:
– Adults and children over 5 years old………………..125 cc
- 4 year old children……………………………………….100 cc
- 3 year old children…………………………………………80 cc
- 1-2 year old children………………………………………60 cc
- over 6 months old children………………………………30 cc
- under 6 months old children…………………………….15 cc
These doses must be administered BY MOUTH. The only contraindication to Magnesium Chloride Therapy is a severe renal insufficiency. As the magnesium chloride has a mild laxative effect, diarrhea sometimes appears on the first days of therapy, especially when high dosages (i.e. three doses a day) are taken; but this is not a reason to stop the therapy.
The taste of the solution is not very good (it has a bitter-saltish flavor) so a little of fruit juice (grapefruit, orange, lemon) can be added to the solution, or it can be even used in the place of water to make the solution itself.
Grapefruit juice masks the bitter taste very well (especially if cold).
For CHRONIC diseases the standard treatment is one dose morning and evening for a long period (several months at least, but it can be continued for years).
In ACUTE diseases the dose is administered every 6 hours (every 3 hours the first two doses if the case is serious); then space every 8 hours and then 12 hours as improvement goes on. After recovery it’s better going on with a dose every 12 hours for some days.
As a PREVENTIVE measure, and as a magnesium supplement, one dose a day can be taken indefinitely. Magnesium Chloride, even if it’s an inorganic salt, is very well absorbed and it’s a very good supplemental magnesium source.
For INTRAVENOUS injection, the formula is:
Magnesium Chloride hexahydrate……………………25 grams
Distilled Water……………………………………………100 cc
Make injections of 10-20cc (very slowly, over 10-20 minutes) once or twice a day. Of course the solution must be sterilized.
This therapy gives very good results also in Veterinary Medicine, at the appropriate dosages depending upon the size and kind of animals.
Raul Vergini, M.D. – Italy – author of: “Curarsi con il Magnesio” Red Edizioni -Italy 1994. http://www.mgwater.com/vergini.shtml
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Tags: abscesses, acne, acute and chronic conjunctivitis, allergies, allergy, asthma, boils, bronchitis, broncho-pneumonia, cancer, chilblains, Chronic Fatigue Syndrome, chronic masitis, colitis, common cold, depression, eczema, external wounds, gastroenterisits, hay fever, herpes zoster, impotence, influenza, measles, mumps, osteomyelitis, Parkinson's disease, pharyngitis, psoriasis, rheumatism, rubella, scarlet fever, tonsillitis, transdermal magnesium, whooping cough |
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Magnesium Linked To Aging Mystery & Calcifications
Magnesium Linked To Aging Mystery & Calcifications
http://www.mgwater.com/agingcal.shtml
By Dr. H. Ray Evers
The average American consumes only 40 percent of the recommended daily allowance of magnesium. This has serious consequences, including death, in many people, according to magnesium expert Dr. Mildred Seelig. Eighty to 90 percent of the U.S. population is magnesium deficient.
Dr. John Prutting said in an issue of “Family Circle” that 70 percent of Americans had mismanaged their diets enough to have some degree of magnesium deficiency.
Magnesium activates 76 percent of the enzymes in the body according to Dr. Sonni Alvarez. Potassium is primarily concerned with the way we use calcium and sodium.
Every doctor knows about the dangers of potassium deficiency, but few recognize that almost half of the patients with a potassium deficiency will also be depleted of magnesium In fact, the low potassium state often cannot be easily corrected unless magnesium is also given.
Most mineral deficiencies stimulate an appetite for the deficient mineral, but there is no “specific appetite” for magnesium Although intravenous magnesium is the drug of choice at the onset of a heart attack, it is not mentioned in the section on arrhythmias in the 1989 “Compendium of Drug Therapy.”
Magnesium is useful in preventing unwanted calcification in the kidney, bladder and in the joints.
If a diet is high in phosphorus (common in many meat dishes as lunchmeats, hot dogs, etc. and also in soda drinks), the phosphate binds up the magnesium into magnesium phosphate, which isn’t absorbed. Thus, you need more magnesium for complete balance.
In disease and stress states, more magnesium is needed. If a person is using diuretics (water pills), he should make sure his magnesium intake is adequate. Potassium supplementation is usually needed also. The higher the protein you consumer the more magnesium is needed. When large amounts of calcium are consumed, you need more magnesium.
Rabbits just can’t take a high-cholesterol diet. Their blood fat level goes up, and they get severe arteriosclerosis/atherosclerosis. However, if you feed them five times the recommended daily allowance of magnesium, their cholesterol goes down and they don’t get arteriosclerosis.
Magnesium is a very important ingredient of the green coloring matter in plants (chlorophyll). Magnesium helps in the use of fat in the diet. In many cases of individuals suffering from irritability, the blood has shown low values for magnesium.
Normal development apparently depends on the presence of magnesium. Approximately 70 percent of the magnesium in the body is found in the skeletal system. At least half of the magnesium in the body is combined with calcium and phosphorus in the bones. The remainder is in the muscles, red blood cells and the other tissues of the body.
Magnesium ensures the strength and firmness of the bones, and it makes the teeth harder. Adequate intake of magnesium counteracts acidity, poor circulation and glandular disorders. Children with magnesium deficiency are very often mentally backward.
Influences On Absorption
The absorption of magnesium from the intestines may be influenced by (1) the parathyroid hormone, (2) the condition of the intestines, (3) the rate of water absorption, and (4) the amounts of calcium, phosphate and lactose (milk sugar) in the body.
Recent studies have shown that magnesium deficiency is found in 25 percent of eating disorders, such as obesity and anorexia nervosa. Symptoms such as weakness, leg cramps, anxiety and confusion will often clear up with magnesium therapy. A magnesium deficiency in humans can occur in patients with diabetes, chronic diarrhea or vomiting.
Heart palpitations, “flutters” or racing heart, otherwise called arrhythmias, usually clear up quite dramatically on 500 milligrams of magnesium citrate (or aspartate) once or twice daily or faster if given intravenously.
The optimal daily requirement for children of 20 kilograms of body weight is 0.25 grams (a kilo is 1,000 grams, equal to 2.2046 lbs). A child of 20 kilos would weigh 44.09 lbs, and for an adult of 70 kilos the requirement is 0.35 grams. The recommended daily allowance is approximately 200 to 300 mg for men and 300 mg for women, although specific requirements depend upon body size.
High-Calcium Dangers
A diet which is high in calcium increases the body’s need for magnesium and also may increase the excretion of phosphorus and calcium; however, dietary intake of magnesium remains relatively low. The chemical reaction of magnesium is alkaline (acid binding). It regulates the acid-alkaline balance of the body.
Magnesium is one of the nutrients needed to lose weight. Undulant fever is said to clear up if above-adequate amounts of magnesium and manganese are given.
Without sufficient magnesium, one cannot control the adrenals, and this lack of control can result in diabetes, hyperexcitability, nervousness, mental confusion and difficulty coping with simple day-to-day problems. Depressed and suicidal people often display inadequate levels of magnesium.
Magnesium helps induce passage of nutrients in and out of cells and thus affects the life process. It also controls metabolism of proteins, fats, and carbohydrates, resulting in more normal nutritional levels. Japanese investigators have discovered that magnesium will relieve asthmatic attacks. They give it intravenously for acute asthma and orally for prevention.
Human Cell’s Power Plant
The power plant of human cell is called the “mitochondrion.” The mitochondrion is what generates energy for the cell to use. What everyone refers to as “energy” is derived from the oxidative reduction of the cellular respiration. This is done through the mitochondria.
But the problem arises when the cell is low in magnesium, relative to calcium. Adenosine triphosphate, the “energy currency” of the cell, is magnesium dependent. This means it is obvious that the calcium pump at the cell membrane is also magnesium dependent.
Without enough “biologically available” magnesium, the cellular calcium pump slows down. Thus a vicious cycle is established. The low levels of available magnesium inhibit the generation of energy, and the low levels of energy inhibit the calcium pump.
The end result? The mitochondrion, the powerhouse of the cell and the entire body, becomes calcified. This is the beginning of aging. It all starts in the cell. First the cells age. This leads to organ aging. And after the organs age, individual aging occurs. Since calcium is readily accumulated by mitochondria, this ion is potentially capable of antagonizing the activating influence of magnesium on many intramitochondrial enzyme reactions.
This means that every function of your body can be inhibited when the mitochondria calcify. It’s like going through life with the emergency brakes on. Calcium is the brake. Magnesium is the accelerator. To be in optimal health, there must be a balance between the two.
Balance Is Key
Both minerals are vitally important, but there must be that critical balance.
Andre Voisin in his book “Soil, Grass and Cancer” wrote: “Calcium content cannot be considered separately without taking the other mineral elements into account. It is the equilibria, and not the individual elements, that govern the phenomena of life.” That’s the magic word – “equilibria.”
Everyone today is concerned with their chronological age. But they should be equally concerned with their “biological” age. The ratio of calcium to magnesium within your cells is your “biochemical age.”
Tragically, in many cases, children are now starting to show high cellular calcium levels. For many people, eating a diet high in calcium and low in magnesium amounts to “cellular suicide.”
Calcification can cause a thousand illnesses. As the body grows, the calcium migrates from the hard tissues (bones) to the soft tissues in your body. Few understand the full scope of this program. It is the most prevalent clinical finding in industrial cultures.
Where the calcium buildup occurs depends upon your individual biochemistry. Calcium deposits in the joints are called arthritis; in the blood vessels it is hardening of the arteries; in the heart it is heart disease, and in the brain it is senility.
The calcification process develops slowly. It occurs gradually over 10, 20, 30 years or more. It can begin in childhood. There is almost no soft tissue in your body that is immune from calcification, including your various glands.
All of this fits so well with my basic belief in medicine, which rests upon the word “balance” – mental, spiritual and physical balance. If we have perfect peace of mind and soul and eat a nutritional poison-free diet, we will have no disease, because, after all, each of us in a scientific sense, is a chemical factory.
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Tags: acid-alkaline balance, acute asthma, Aging, anorexia nervosa, arrhythmia, arthritis, asthma, calcification, diabetes, high acidity, high cholesterol, Inflammation, magnesium, magnesium calcium, mental disorders magnesium, stress, transdermal magnesium |
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Nebulizing Magnesium and other Medicinals
Sometimes very sick people or even animals with a lung ailment do better when taking drugs by nebulization as opposed to orally, because then the embattled system doesn’t need to go through breaking down the medications in the stomach and then delivering them to the lungs through the blood stream. With nebulization medicines get sprayed directly onto the lung tissues where they can most easily be absorbed locally by the lung and brachial cells.
Dr. Shallenberger says, “A nebulizer is able to convert a liquid into tiny bubbles that are so tiny that they can only be seen under a microscope. When these bubbles come out of the nebulizer, they are so small that they look just like smoke. And that’s the magic of a nebulizer. The bubbles are so small that they can be inhaled deep down into the deepest regions of the lungs without any discomfort or irritation. It’s a great way for asthmatics to get the medication they need to open up their lungs.”
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Get More Magnesium, Get Smarter
The US National Institute of Health recommends adults get 300-420 mg of magnesium each day depending on gender. It’s found in leafy greens, fruits, nuts, and whole grains. Yet most of us probably don’t get these daily doses. Even when you do get magnesium in your diet, it may not get to your brain in sufficient quantities to boost mental function. Your body has to actively ‘pump’ magnesium into your cerebrospinal fluid. You can’t just increase the amount of magnesium in your blood, you have to make it easier to get to the brain.
That’s why Guosong Liu and others involved in the rats study developed MgT. Back in 2004, Liu and fellow researchers published work detailing how that magnesium may positively affect the cognitive abilities of rats. That work led them to try and find a chemical compound with magnesium that is more easily ‘pumped’ into the cerebrospinal fluid. The compound turned out to be MgT, and its effects on rats are amazing.
Magnesium Therapy Helps Asthmatics
Dr John Briffa says:
“Magnesium therapy was tried in a study published recently in the Journal of Asthma [1]. In it, 55 adults with mild-moderate asthma were treated with magnesium (170 mg, twice a day) or placebo over a period of 6.5 months. Individuals had their lung function tested using peak expiratory flow (the maximum speed air can be expelled from the lungs) as well as something known as the methacholine challenge test. Metacholine causes constriction of airways. In this test, subjects breath in metacholine and the dose of this drug required to induce constriction in the airways. The higher the dose of metacholine required, the less ‘reactive’ the airways would be judged to be.
Compared to those taking placebo, those taking magnesium saw significant improvement in both their peak expiratory flow rate and metacholine challenge results”
http://www.drbriffa.com/blog/2010/01/29/magnesium-therapy-found-to-benefit-asthmatics/
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Magnesium and Inflammation
Dr. Michael Eades has this to say about Magnesium and inflammation:
The lipid hypothesis of heart disease is rapidly being supplanted by the inflammatory hypothesis, which, for my money, is much more on the mark. The researchers who have spent their careers doing cholesterol research are not going down without a fight, however. Whereas most of the speakers at medical conferences always used to show graphs demonstrating that as cholesterol levels went up, so did the risk for heart disease. Now most speakers are showing graphs demonstrating that elevated cholesterol in combination with an elevated C-reactive protein (a measure of inflammation) is a better gauge of heart disease risk. I predict that over the next few years, the cholesterol part of these graphs will slowly disappear.
As the inflammatory hypothesis becomes more accepted, more and more physicians will be checking C-reactive protein levels along with a few other inflammatory yardsticks to determine the inflammatory status of their patients. If the C-reactive protein level is found to be elevated, then steps can be taken, not just to reduce the C-reactive protein, but to treat the underlying inflammation so that the C-reactive protein a marker of this underlying inflammation will normalize.
One easy step in the inflammation reduction process is to make sure magnesium intake is high. (emphasis mine)
And here is another article on the subject:
Magnesium – The Anti-Inflammatory Mineral
Tuesday, November 24, 2009 – Byron Richards, CCN
A new study of 3,713 postmenopausal women shows that magnesium is a powerful anti-inflammatory nutrient. Each 100 mg of magnesium per day was associated with a significant reduction in various inflammatory markers.
Magnesium is the most lacking mineral in the human diet. This is due primarily to Big Agribusiness farming practices that have stripped our soils of vital minerals needed for human health. It is complicated by processed diets lacking in magnesium-containing fresh fruits and vegetables. When you consider that inflammation is behind almost all health problems the consequence of eating a magnesium deficient diet becomes obvious.
The study showed that inflammatory markers such as CRP (C-reactive protein), TNFa (tumor necrosis factor alpha), and IL6 (interleukin 6) were all reduced when magnesium intake was higher. These are common inflammatory markers that are often elevated with the diseases of aging.
Furthermore, various inflammatory markers relating to the walls of arteries were also reduced when magnesium was adequate. Inflammation on the lining of the arteries is required for plaque formation. Reducing such inflammation is highly protective to arterial health.
It is not a stretch to say that if public health officials did nothing other than ensure vitamin D and magnesium sufficiency the entire health of a nation would be drastically improved and health care costs would be significantly lower.
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Magnesium Aids Digestion
Dr. John Briffa says:
I remember once attending a nutritional therapy course for doctors in the US, in which one of the facilitators (Dr Jonathan Wright) said, “If it spasms, think magnesium” (or something similar). And this sagely piece of advice was based on the idea that low levels of magnesium in the body tend to cause muscle to go into spasm. This might include so-called ‘smooth’ muscle in, say, the digestive tract, bladder on in the walls of the arteries. It might also include ‘skeletal’ muscle, say, in the legs. Ever since hearing learning this I’ve used magnesium generally very effectively to treat conditions like muscular cramps, ‘restless legs’, irritable bladder syndrome and oesophageal spasm.
So, with this I mind I suggested that my family member supplement with magnesium to see if this helps his symptoms. In short, it did. Within a day or two of taking magnesium, the epigastric discomfort that had plagued him on a daily basis for years disappeared, and has seemingly not returned some 10 days later.
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