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	<title>Magnesium Oil - Transdermal Magnesium &#187; Inflammation</title>
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	<description>Magnesium Chloride Information</description>
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		<title>Bishofit &#8211; Magnesium Oil from Russia</title>
		<link>http://www.magnesiumoil.org.uk/2010/05/bishofit-magnesium-oil-from-russia/</link>
		<comments>http://www.magnesiumoil.org.uk/2010/05/bishofit-magnesium-oil-from-russia/#comments</comments>
		<pubDate>Wed, 26 May 2010 09:18:20 +0000</pubDate>
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				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[Aging]]></category>
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		<guid isPermaLink="false">http://www.magnesiumoil.org.uk/?p=279</guid>
		<description><![CDATA[
Bishofit is a name for magnesium chloride salt which was formed millions of years ago as a result of evaporation of ancient seas. It lies deep underground &#8211; and is obtained by dissolving the crystals in water and pumping up the saturated solution. In this respect Bishofit has the same origin as Zechstein magnesium. It [...]]]></description>
			<content:encoded><![CDATA[<p></br><br />
Bishofit is a name for magnesium chloride salt which was formed millions of years ago as a result of evaporation of ancient seas. It lies deep underground &#8211; and is obtained by dissolving the crystals in water and pumping up the saturated solution. In this respect Bishofit has the same origin as Zechstein magnesium. It owes its name to a German chemist Gustav Bischof who first discovered underground deposits of magnesium chloride in 19th century. </p>
<p>The main constituent of Bishofit in its liquid form is Magnesium Chloride hexahydrate, some calcium sulphate, calcium chloride, calcium hydrocarbonate, sodium chloride,  and of course water, with the overall mineral content of 400-450g per 1 litre of water. Additionally, Bishofit contains sodium, iodine, iron, bromide, silica, molybdenum, titanium, lithium, as well as traces of almost all the chemical elements of the Periodic Table.</p>
<p><strong>Healing Properties of Bishofit</strong></p>
<p>People have known about the healing properties of Bishofit for a long time and have been using it to treat muscle cramps, aches and pains, to calm nerves, relax, etc. It is widely used in balneology due to its analgesic and anti-inflammatory effect to treat osteoarthritis, rheumatoid arthritis,  lumbago, and other conditions of the Musculo-skeletal and Nervous systems.  It is also used to treat nervous tension, stress, a variety of skin conditions and a number of other problems.</p>
<p>Bishofit (Magnesium Chloride solution)  is widely used in medicine for a number of pharmacological properties.</p>
<p>It has been found to:</p>
<p>    * Stimulate protein/fat metabolism<br />
    * Reduce inflammation by lowering the levels of histamine and serotonin (mediators of inflammation)<br />
    * Speed up rehabilitation processes in the body<br />
    * Increase testosterone levels and sperm production<br />
    * Increase metabolic rate<br />
    * Strengthen immunity<br />
    * Slow down ageing<br />
    * Reduce cholesterol levels in the blood<br />
    * Improve the functioning of the Musculo-Skeletal system<br />
    * Reduce blood pressure<br />
    * Reduce symptoms of hay fever and allergies<br />
    * Significantly reduce heart disease and mortality<br />
    * Lower the incidence of cancers<br />
    * Improve the functioning of the Nervous System<br />
    * Reduce the effects of stress<br />
    * Increase phagocytosis<br />
    * Speed up tissue regeneration<br />
    * Improve skin condition<br />
    * Help with respiratory conditions, such as bronchitis, asthma, whooping-cough,<br />
       chronic respiratory complaints.</p>
<p>It has been proved to be a:</p>
<p>    * Sedative<br />
    * Anti-inflammatory<br />
    * Bactericidal / fungicidal<br />
    * Improve micro-circulation<br />
    * Analgesic<br />
    * Immune regulator</p>
<p>The scientists of the Volgograd Medical Academy have been working on the research of  Bishofit  for over 20 years. The mineral has been approved in Russia as a balneological remedy. Considering the wide use of Bishofit in the treatment of various ailments in Russia, as well as its close similarity to a variety of medical products, a number of balneological products based on Bishofit have been developed. Russian scientists are working on pharmacological preparations based on Bishofit.<br />
</br><br />
<b>Physical Properties &#038; Chemical Composition of the  Bishofit solution (Volgograd, Russia)</b><br />
</br></p>
<p>Density, g/l &#8211; 1.320-1.330<br />
ρН &#8211; 7.8<br />
Mineral content, g/l &#8211; 400-450</p>
<p>Salt content ( %) in dry matter:</p>
<p>Mg Cl2× 6H2O &#8211; 90-96<br />
Mg SO4× H2O &#8211; 0.1-2.5<br />
Mg(HCO3)2<br />
MgBr2 &#8211; 0.4-0.95<br />
NaCl &#8211; 0.1-0.4<br />
CaCl2<br />
CaBr2<br />
CaSO4 &#8211; 0.1-0.7<br />
KCl× MgCl2× 6H2O &#8211; 0.1-5.5</p>
<p>Microelements (%):</p>
<p>Fe &#8211; 0.003-0.03<br />
Bi &#8211; 0.0005-0.001<br />
Mo &#8211; 0.0005-0.001<br />
B &#8211; 0.002-0.08<br />
Al &#8211; 0.001-0.02<br />
Ti &#8211; 0.0005-0.001<br />
Cu &#8211; 0.0001-0.0006<br />
Si &#8211; 0.02-0.2<br />
Ba &#8211; 0.0001-0.0006<br />
Sr &#8211; 0.001-0.02<br />
Co &#8211; 0.003-0.005<br />
Rb &#8211; 0.0001-0.002<br />
Cs &#8211; 0.0001-0.001<br />
Li &#8211; 0.0001-0.0003</p>
<p><strong>Read <b><a href="http://www.naturalrussia.com/natural/bishofit/bishofit_info.html"> the full article about Bishofit</b></a></p>
<p><b><a href="http://www.naturalrussia.com/natural/index.html">Buy Bishofit</a></b></p>
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		<title>Magnesium in the management of asthma</title>
		<link>http://www.magnesiumoil.org.uk/2010/04/magnesium-in-the-management-of-asthma/</link>
		<comments>http://www.magnesiumoil.org.uk/2010/04/magnesium-in-the-management-of-asthma/#comments</comments>
		<pubDate>Thu, 15 Apr 2010 15:27:02 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[Uncategorized]]></category>
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		<guid isPermaLink="false">http://www.magnesiumoil.org.uk/?p=268</guid>
		<description><![CDATA[Harari M, Barzillai R, Shani J.
The recognition of asthma as an inflammatory disease has led over the past 20 years to a major shift in its pharmacotherapy. The previous emphasis on using relatively short-acting agents for relieving bronchospasms and for removing bronchial mucus has shifted toward long-term strategies with the use of inhaled corticosteroids, which [...]]]></description>
			<content:encoded><![CDATA[<p>Harari M, Barzillai R, Shani J.</p>
<p>The recognition of asthma as an inflammatory disease has led over the past 20 years to a major shift in its pharmacotherapy. The previous emphasis on using relatively short-acting agents for relieving bronchospasms and for removing bronchial mucus has shifted toward long-term strategies with the use of inhaled corticosteroids, which successfully prevent and abolish airway inflammation. Because some of the biological, chemical, and immunological processes that characterize asthma also underlie arthritis and other inflammatory diseases, and because many of these conditions have been successfully treated for the past 40 years at the Dead Sea, we were not surprised to realize and record the significant improvement of asthmatic condition after a 4-week stay at the Dead Sea: lung function was improved, the number and severity of attacks was reduced, and the efficacy of beta2-agonist treatments was improved. After reviewing the acute and chronic treatments of asthma in the clinic (including emergency rooms) with magnesium compounds, and the use of such salts as supplementary agents in respiratory diseases, we suggest that the improvement in the asthmatic condition at the Dead Sea may be due to absorption of this element through the skin and via the lungs, and due to its involvement in anti-inflammatory and vasodilatatory processes&#8221;.</p>
<p><a href=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed&#038;cmd=Retrieve&#038;list_uids=9777879&#038;dopt=Abstract><b> Abstract from a scientific study at DMZ Rehabilitation Clinic, Ein-Bokek, The Dead Sea, Israel)</b></a><br />
</br></p>
<p><strong>More articles about magnesium<strong><br />
</br><br />
<a href=" http://www.naturalrussia.com/natural/bishofit/magnesium_articles.html">www.naturalrussia.com</a><br />
</br><br />
<a href="http://www.mgwater.com">www.mgwater.com</a></strong></p>
<p><a href="http://www.naturalrussia.com"><b>Buy magnesium products</b></a></p>
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		<title>Magnesium Linked To Aging Mystery &amp; Calcifications</title>
		<link>http://www.magnesiumoil.org.uk/2010/03/magnesium-linked-to-aging-mystery-calcifications/</link>
		<comments>http://www.magnesiumoil.org.uk/2010/03/magnesium-linked-to-aging-mystery-calcifications/#comments</comments>
		<pubDate>Mon, 29 Mar 2010 21:22:45 +0000</pubDate>
		<dc:creator>admin</dc:creator>
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		<guid isPermaLink="false">http://www.magnesiumoil.org.uk/?p=214</guid>
		<description><![CDATA[The balance of magnesium and calcium is vital in prevention of ageing. Adenosine triphosphate, the "energy currency" of the cell, is magnesium dependent. This means it is obvious that the calcium pump at the cell membrane is also magnesium dependent.

Without enough "biologically available" magnesium, the cellular calcium pump slows down. Thus a vicious cycle is established. The low levels of available magnesium inhibit the generation of energy, and the low levels of energy inhibit the calcium pump. The end result? The mitochondrion, the powerhouse of the cell and the entire body, becomes calcified. This is the beginning of aging. It all starts in the cell. First the cells age. This leads to organ aging. And after the organs age, individual aging occurs.]]></description>
			<content:encoded><![CDATA[<h2>Magnesium Linked To Aging Mystery &amp;   Calcifications</h2>
<p>http://www.mgwater.com/agingcal.shtml</p>
<h3>By Dr. H. Ray Evers</h3>
<p>The average American consumes only 40 percent of the   recommended daily allowance of magnesium. This has serious   consequences, including death, in many people, according to   magnesium expert Dr. Mildred Seelig. Eighty to 90 percent of the   U.S. population is magnesium deficient.</p>
<p>Dr. John Prutting said in an issue of &#8220;Family Circle&#8221; that 70   percent of Americans had mismanaged their diets enough to have   some degree of magnesium deficiency.</p>
<p>Magnesium activates 76 percent of the enzymes in the body   according to Dr. Sonni Alvarez. Potassium is primarily concerned   with the way we use calcium and sodium.</p>
<p>Every doctor knows about the dangers of potassium deficiency,   but few recognize that almost half of the patients with a   potassium deficiency will also be depleted of magnesium In fact,   the low potassium state often cannot be easily corrected unless   magnesium is also given.</p>
<p>Most mineral deficiencies stimulate an appetite for the   deficient mineral, but there is no &#8220;specific appetite&#8221; for   magnesium Although intravenous magnesium is the drug of choice at   the onset of a heart attack, it is not mentioned in the section   on arrhythmias in the 1989 &#8220;Compendium of Drug Therapy.&#8221;</p>
<p>Magnesium is useful in preventing unwanted calcification in   the kidney, bladder and in the joints.</p>
<p>If a diet is high in phosphorus (common in many meat dishes as   lunchmeats, hot dogs, etc. and also in soda drinks), the   phosphate binds up the magnesium into magnesium phosphate, which   isn&#8217;t absorbed. Thus, you need more magnesium for complete   balance.</p>
<p>In disease and stress states, more magnesium is needed. If a   person is using diuretics (water pills), he should make sure his   magnesium intake is adequate. Potassium supplementation is   usually needed also. The higher the protein you consumer the more   magnesium is needed. When large amounts of calcium are consumed,   you need more magnesium.</p>
<p>Rabbits just can&#8217;t take a high-cholesterol diet. Their blood   fat level goes up, and they get severe   arteriosclerosis/atherosclerosis. However, if you feed them five   times the recommended daily allowance of magnesium, their   cholesterol goes down and they don&#8217;t get arteriosclerosis.</p>
<p>Magnesium is a very important ingredient of the green coloring   matter in plants (chlorophyll). Magnesium helps in the use of fat   in the diet. In many cases of individuals suffering from   irritability, the blood has shown low values for magnesium.</p>
<p>Normal development apparently depends on the presence of   magnesium. Approximately 70 percent of the magnesium in the body   is found in the skeletal system. At least half of the magnesium   in the body is combined with calcium and phosphorus in the bones.   The remainder is in the muscles, red blood cells and the other   tissues of the body.</p>
<p>Magnesium ensures the strength and firmness of the bones, and   it makes the teeth harder. Adequate intake of magnesium   counteracts acidity, poor circulation and glandular disorders.   Children with magnesium deficiency are very often mentally   backward.</p>
<h3>Influences On Absorption</h3>
<p>The absorption of magnesium from the intestines may be   influenced by (1) the parathyroid hormone, (2) the condition of   the intestines, (3) the rate of water absorption, and (4) the   amounts of calcium, phosphate and lactose (milk sugar) in the   body.</p>
<p>Recent studies have shown that magnesium deficiency is found   in 25 percent of eating disorders, such as obesity and anorexia   nervosa. Symptoms such as weakness, leg cramps, anxiety and   confusion will often clear up with magnesium therapy. A magnesium   deficiency in humans can occur in patients with diabetes, chronic   diarrhea or vomiting.</p>
<p>Heart palpitations, &#8220;flutters&#8221; or racing heart, otherwise   called arrhythmias, usually clear up quite dramatically on 500   milligrams of magnesium citrate (or aspartate) once or twice   daily or faster if given intravenously.</p>
<p>The optimal daily requirement for children of 20 kilograms of   body weight is 0.25 grams (a kilo is 1,000 grams, equal to 2.2046   lbs). A child of 20 kilos would weigh 44.09 lbs, and for an adult   of 70 kilos the requirement is 0.35 grams. The recommended daily   allowance is approximately 200 to 300 mg for men and 300 mg for   women, although specific requirements depend upon body size.</p>
<h3>High-Calcium Dangers</h3>
<p>A diet which is high in calcium increases the body&#8217;s need for   magnesium and also may increase the excretion of phosphorus and   calcium; however, dietary intake of magnesium remains relatively   low. The chemical reaction of magnesium is alkaline (acid   binding). It regulates the acid-alkaline balance of the body.</p>
<p>Magnesium is one of the nutrients needed to lose weight.   Undulant fever is said to clear up if above-adequate amounts of   magnesium and manganese are given.</p>
<p>Without sufficient magnesium, one cannot control the adrenals,   and this lack of control can result in diabetes,   hyperexcitability, nervousness, mental confusion and difficulty   coping with simple day-to-day problems. Depressed and suicidal   people often display inadequate levels of magnesium.</p>
<p>Magnesium helps induce passage of nutrients in and out of   cells and thus affects the life process. It also controls   metabolism of proteins, fats, and carbohydrates, resulting in   more normal nutritional levels. Japanese investigators have   discovered that magnesium will relieve asthmatic attacks. They   give it intravenously for acute asthma and orally for   prevention.</p>
<h3>Human Cell&#8217;s Power Plant</h3>
<p>The power plant of human cell is called the &#8220;mitochondrion.&#8221;   The mitochondrion is what generates energy for the cell to use.   What everyone refers to as &#8220;energy&#8221; is derived from the oxidative   reduction of the cellular respiration. This is done through the   mitochondria.</p>
<p>But the problem arises when the cell is low in magnesium,   relative to calcium. Adenosine triphosphate, the &#8220;energy   currency&#8221; of the cell, is magnesium dependent. This means it is   obvious that the calcium pump at the cell membrane is also   magnesium dependent.</p>
<p>Without enough &#8220;biologically available&#8221; magnesium, the   cellular calcium pump slows down. Thus a vicious cycle is   established. The low levels of available magnesium inhibit the   generation of energy, and the low levels of energy inhibit the   calcium pump.</p>
<p>The end result? The mitochondrion, the powerhouse of the cell   and the entire body, becomes calcified. This is the beginning of   aging. It all starts in the cell. First the cells age. This leads   to organ aging. And after the organs age, individual aging   occurs. Since calcium is readily accumulated by mitochondria,   this ion is potentially capable of antagonizing the activating   influence of magnesium on many intramitochondrial enzyme   reactions.</p>
<p>This means that every function of your body can be inhibited   when the mitochondria calcify. It&#8217;s like going through life with   the emergency brakes on. Calcium is the brake. Magnesium is the   accelerator. To be in optimal health, there must be a balance   between the two.</p>
<h3>Balance Is Key</h3>
<p>Both minerals are vitally important, but there must be that   critical balance.</p>
<p>Andre Voisin in his book &#8220;Soil, Grass and Cancer&#8221; wrote:   &#8220;Calcium content cannot be considered separately without taking   the other mineral elements into account. It is the equilibria,   and not the individual elements, that govern the phenomena of   life.&#8221; That&#8217;s the magic word &#8211; &#8220;equilibria.&#8221;</p>
<p>Everyone today is concerned with their chronological age. But   they should be equally concerned with their &#8220;biological&#8221; age. The   ratio of calcium to magnesium within your cells is your   &#8220;biochemical age.&#8221;</p>
<p>Tragically, in many cases, children are now starting to show   high cellular calcium levels. For many people, eating a diet high   in calcium and low in magnesium amounts to &#8220;cellular   suicide.&#8221;</p>
<p>Calcification can cause a thousand illnesses. As the body   grows, the calcium migrates from the hard tissues (bones) to the   soft tissues in your body. Few understand the full scope of this   program. It is the most prevalent clinical finding in industrial   cultures.</p>
<p>Where the calcium buildup occurs depends upon your individual   biochemistry. Calcium deposits in the joints are called   arthritis; in the blood vessels it is hardening of the arteries;   in the heart it is heart disease, and in the brain it is   senility.</p>
<p>The calcification process develops slowly. It occurs gradually   over 10, 20, 30 years or more. It can begin in childhood. There   is almost no soft tissue in your body that is immune from   calcification, including your various glands.</p>
<p>All of this fits so well with my basic belief in medicine,   which rests upon the word &#8220;balance&#8221; &#8211; mental, spiritual and   physical balance. If we have perfect peace of mind and soul and   eat a nutritional poison-free diet, we will have no disease,   because, after all, each of us in a scientific sense, is a   chemical factory.</p>
<p></small></big><br />
</br><br />
</br><br />
<strong>More articles about magnesium<strong><br />
</br><br />
<a href=" http://www.naturalrussia.com/natural/bishofit/magnesium_articles.html">www.naturalrussia.com</a><br />
</br><br />
<a href="http://www.mgwater.com">www.mgwater.com</a></strong><br />
</br><br />
<a href="http://www.naturalrussia.com"><b>Buy magnesium products</b></a><br />
</br></p>
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		<title>Magnesium and Inflammation</title>
		<link>http://www.magnesiumoil.org.uk/2010/01/magnesium-and-inflammation/</link>
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		<pubDate>Mon, 11 Jan 2010 10:40:06 +0000</pubDate>
		<dc:creator>admin</dc:creator>
				<category><![CDATA[magnesium]]></category>
		<category><![CDATA[cardiac]]></category>
		<category><![CDATA[cholesterol]]></category>
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		<category><![CDATA[Inflammation]]></category>

		<guid isPermaLink="false">http://www.magnesiumoil.org.uk/?p=190</guid>
		<description><![CDATA[Dr. Michael Eades has this to say about Magnesium and inflammation:
The lipid hypothesis of heart disease is rapidly being supplanted by the inflammatory hypothesis, which, for my money, is much more on the mark. The researchers who have spent their careers doing cholesterol research are not going down without a fight, however. Whereas most of [...]]]></description>
			<content:encoded><![CDATA[<p><a title="Magnesium and Inflammation" href="http://www.proteinpower.com/drmike/uncategorized/magnesium-and-inflammation/" target="_blank">Dr. Michael Eades</a> has this to say about Magnesium and inflammation:</p>
<p>The lipid hypothesis of heart disease is rapidly being supplanted by the inflammatory hypothesis, which, for my money, is much more on the mark. The researchers who have spent their careers doing cholesterol research are not going down without a fight, however. Whereas most of the speakers at medical conferences always used to show graphs demonstrating that as cholesterol levels went up, so did the risk for heart disease. Now most speakers are showing graphs demonstrating that elevated cholesterol in combination with an elevated C-reactive protein (a measure of inflammation) is a better gauge of heart disease risk. I predict that over the next few years, the cholesterol part of these graphs will slowly disappear.</p>
<p>As the inflammatory hypothesis becomes more accepted, more and more physicians will be checking C-reactive protein levels along with a few other inflammatory yardsticks to determine the inflammatory status of their patients. If the C-reactive protein level is found to be elevated, then steps can be taken, not just to reduce the C-reactive protein, but to treat the underlying inflammation so that the C-reactive protein a marker of this underlying inflammation will normalize.</p>
<p><em>One easy step in the inflammation reduction process is to make sure magnesium intake is high. </em>(emphasis mine)<br />
</br><br />
</br></p>
<p>And here is another article on the subject:</p>
<p><strong>Magnesium – The Anti-Inflammatory Mineral</strong><br />
<a href="http://www.wellnessresources.com/health/articles/magnesium_the_anti-inflammatory_mineral/"><br />
Tuesday, November 24, 2009 &#8211; Byron Richards, CCN </a></p>
<p>A new study of 3,713 postmenopausal women shows that magnesium is a powerful anti-inflammatory nutrient.  Each 100 mg of magnesium per day was associated with a significant reduction in various inflammatory markers.</p>
<p>Magnesium is the most lacking mineral in the human diet.  This is due primarily to Big Agribusiness farming practices that have stripped our soils of vital minerals needed for human health.  It is complicated by processed diets lacking in magnesium-containing fresh fruits and vegetables.  When you consider that inflammation is behind almost all health problems the consequence of eating a magnesium deficient diet becomes obvious. </p>
<p>The study showed that inflammatory markers such as CRP (C-reactive protein), TNFa (tumor necrosis factor alpha), and IL6 (interleukin 6) were all reduced when magnesium intake was higher.  These are common inflammatory markers that are often elevated with the diseases of aging.</p>
<p>Furthermore, various inflammatory markers relating to the walls of arteries were also reduced when magnesium was adequate.  Inflammation on the lining of the arteries is required for plaque formation.  Reducing such inflammation is highly protective to arterial health.</p>
<p>It is not a stretch to say that if public health officials did nothing other than ensure vitamin D and magnesium sufficiency the entire health of a nation would be drastically improved and health care costs would be significantly lower.<br />
</br><br />
</br><br />
<strong>More articles about magnesium<strong><br />
</br><br />
<a href=" http://www.naturalrussia.com/natural/bishofit/magnesium_articles.html">www.naturalrussia.com</a><br />
</br><br />
<a href="http://www.mgwater.com">www.mgwater.com</a></strong><br />
</br><br />
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		<title>Magnesium, Homoeostasis, and Aging</title>
		<link>http://www.magnesiumoil.org.uk/2009/12/magnesium-homoeostasis-and-ageing/</link>
		<comments>http://www.magnesiumoil.org.uk/2009/12/magnesium-homoeostasis-and-ageing/#comments</comments>
		<pubDate>Wed, 30 Dec 2009 08:39:06 +0000</pubDate>
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				<category><![CDATA[Uncategorized]]></category>
		<category><![CDATA[Ageing]]></category>
		<category><![CDATA[Aging]]></category>
		<category><![CDATA[asthma]]></category>
		<category><![CDATA[cardiac]]></category>
		<category><![CDATA[Chronic fatifue]]></category>
		<category><![CDATA[depression]]></category>
		<category><![CDATA[high blood pressure]]></category>
		<category><![CDATA[Inflammation]]></category>
		<category><![CDATA[stroke]]></category>
		<category><![CDATA[thrombosis]]></category>

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		<description><![CDATA[Magnesium, Homoeostasis, and Aging

Mario Barbagallo, Mario Belvedere, Ligia J Dominguez

Summary : Aging is very often associated with magnesium (Mg) deficit. Total plasma magnesium concentrations are remarkably constant in healthy subjects throughout life, while total body Mg and Mg in the intracellular compartment tend to decrease with age. Dietary Mg deficiencies are common in the elderly [...]]]></description>
			<content:encoded><![CDATA[<p><b>Magnesium, Homoeostasis, and Aging</b><br />
</br><br />
Mario Barbagallo, Mario Belvedere, Ligia J Dominguez<br />
</br><br />
Summary : Aging is very often associated with magnesium (Mg) deficit. Total plasma magnesium concentrations are remarkably constant in healthy subjects throughout life, while total body Mg and Mg in the intracellular compartment tend to decrease with age. Dietary Mg deficiencies are common in the elderly population. Other frequent causes of Mg deficits in the elderly include reduced Mg intestinal absorption, reduced Mg bone stores, and excess urinary loss. Secondary Mg deficit in aging may result from different conditions and diseases often observed in the elderly (i.e. insulin resistance and/or type 2 diabetes mellitus) and drugs (i.e. use of hypermagnesuric diuretics). Chronic Mg deficits have been linked to an increased risk of numerous preclinical and clinical outcomes, mostly observed in the elderly population, including hypertension, stroke, atherosclerosis, ischemic heart disease, cardiac arrhythmias, glucose intolerance, insulin resistance, type 2 diabetes mellitus, endothelial dysfunction, vascular remodeling, alterations in lipid metabolism, platelet aggregation/thrombosis, inflammation, oxidative stress, cardiovascular mortality, asthma, chronic fatigue, as well as depression and other neuropsychiatric disorders. Both aging and Mg deficiency have been associated to excessive production of oxygen-derived free radicals and low-grade inflammation. Chronic inflammation and oxidative stress are also present in several age-related diseases, such as many vascular and metabolic conditions, as well as frailty, muscle loss and sarcopenia, and altered immune responses, among others. Mg deficit associated to aging may be at least one of the pathophysiological links that may help to explain the interactions between inflammation and oxidative stress with the aging process and many age-related diseases.</p>
<p>http://www.john-libbey-eurotext.fr/en/revues/bio_rech/mrh/e-docs/00/04/51/FF/resume.phtml</p>
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